Evolution by Gene Duplication

Voorkant
Springer Science & Business Media, 11 dec. 2013 - 160 pagina's
It is said that "necessity is the mother of invention". To be sure, wheels and pulleys were invented out of necessity by the tenacious minds of upright citi zens. Looking at the history of mankind, however, one has to add that "Ieisure is the mother of cultural improvement". Man's creative genius flourished only when his mind, freed from the worry of daily toils, was permitted to entertain apparently useless thoughts. In the same manner, one might say with regard to evolution that "natural selection mere(y tnodifted, while redundanry created". Natural selection has been extremely effective in policing alleHe mutations which arise in already existing gene loci. Because of natural selection, organisms have been able to adapt to changing environments, and by adaptive radiation many new species were created from a common ancestral form. Y et, being an effective policeman, natural selection is extremely conservative by nature. Had evolution been entirely dependent upon natural selection, from a bacterium only numerous forms of bacteria would have emerged. The creation of metazoans, vertebrates and finally mammals from unicellular organisms would have been quite impos sible, for such big leaps in evolution required the creation of new gene loci with previously nonexistent functions. Only the cistron which became redun dant was able to escape from the relentless pressure of natural selection, and by escaping, it accumulated formerly forbidden mutations to emerge as a new gene locus.
 

Wat mensen zeggen - Een review schrijven

We hebben geen reviews gevonden op de gebruikelijke plaatsen.

Inhoudsopgave

Introduction
1
Chromosomes of Eukaryotes
15
Contents
21
Tolerable Mutations
32
The Conservative Nature of Chromosomal Evolution
41
The Spontaneous Mutation Rate
48
The Rate of Evolution and the Importance of Isolation
55
Duplication of Regulatory Genes and Receptors
82
Contents
89
Duplication of the Entire Genome
98
Other Mechanisms for Achieving Gene Duplication
107
Natures Great Experiment with Gene Duplication during
124
Evolution from Amphibians to Birds and Mammals and
132
Whence Comes Man?
139
Subject Index
147
Copyright

Overige edities - Alles weergeven

Veelvoorkomende woorden en zinsdelen

Bibliografische gegevens