Enzyme Catalysis in Organic Synthesis, 3 Volume SetKarlheinz Drauz, Harald Gröger, Oliver May John Wiley & Sons, 26 mrt 2012 - 2038 pagina's This comprehensive three-volume set is the standard reference in the field of organic synthesis, catalysis and biocatalysis. Edited by a highly experienced and highly knowledgeable team with a tremendous amount of experience in this field and its applications, this edition retains the successful concept of past editions, while the contents are very much focused on new developments in the field. All the techniques described are directly transferable from the lab to the industrial scale, making for a very application-oriented approach. A must for all chemists and biotechnologists. |
Inhoudsopgave
About the Editors | xli |
Contents to Volume | 1 |
Concepts in Biocatalysis | 43 |
Discovery of Enzymes | 67 |
Rational Design of Enzymes | 89 |
Directed Evolution of Enzymes | 119 |
Production and Isolation of Enzymes | 191 |
Reaction and Process Engineering | 217 |
References 107 | 998 |
Hydrolysis and Formation of PO Bonds | 1001 |
Reductions | 1035 |
Reduction of CC Double Bonds | 1111 |
Reductive Amination of Keto Acids | 1165 |
Contents to Volume 3 | xxvii |
Directed Evolution of Enzymes 119 | xlii |
Oxidations | 1225 |
Hydrolysis and Formation of CO Bonds | 249 |
Hydrolysis and Formation of Epoxides | 363 |
Evolution | 381 |
Hydrolysis and Formation of Glycosidic Bonds | 417 |
Addition of Water to CC Bonds and its Elimination | 467 |
Industrial Application and Processes Forming CO Bonds | 503 |
CarbonOxygen Lyases | 513 |
Contents to Volume 2 | xxvii |
Hydrolysis and Formation of CN Bonds | 531 |
Hydrolysis of Nitriles to Carboxylic Acids | 545 |
Hydrolysis of Amides | 561 |
Hydrolysis and Formation of Hydantoins | 651 |
Transformations 17 | 652 |
and its Application | 665 |
17 | 675 |
Catalytic Mechanism | 681 |
3 | 692 |
Peptide Synthesis | 729 |
Application of Transaminases | 779 |
Formation and Cleavage of CC Bonds | 855 |
Cleavage and Formation of Cyanohydrins | 947 |
Industrial Application and Processes Using CarbonCarbon Lyases | 991 |
Oxidation of Alcohols Aldehydes and Acids | 1325 |
1 2 23 872 | 1335 |
Specificity 717 | 1348 |
Transformations 17 | 1369 |
BaeyerVilliger Oxidations | 1439 |
Aromatic Oxidations | 1487 |
Oxidation of CN Bonds | 1535 |
Oxidation at Sulfur and Oxidation of Amino Groups | 1553 |
Organisms | 1554 |
Halogenation | 1569 |
Industrial Application and Processes Using Biocatalysts | 1585 |
Industrial Application and Processes Using Isomerases | 1685 |
Extended Applications of Enzyme Catalysis | 1693 |
Catalytic Antibodies | 1735 |
Chemoenzymatic Dynamic Kinetic Resolution and Related | 1777 |
Biocatalysis in Material Science | 1807 |
Industrial Applications of Enzymes in Emerging Areas | 1837 |
Tabular Survey of Available Enzymes | 1847 |
28 | 1917 |
29 | 1927 |
1939 | |
Veelvoorkomende woorden en zinsdelen
acceptor activity acyl alcohols aldehydes aldol aldolase aliphatic amidase amine amino acid aminopeptidase Angew Appl application aromatic asymmetric asymmetric synthesis Bacillus binding biocatalyst Biochem Biochemistry Biol Biotechnol biotransformation carboxylic Catal catalyzed Chem chemical Chemistry chiral CO₂H cofactor compounds conversion COOH dehydratase dehydrogenase desymmetrization diol directed evolution donor efficient enantiomer enantiomeric enantioselectivity engineering enzymatic enzymatic resolution enzyme epoxide hydrolase epPCR Escherichia coli ester esterase example formation function gene halohydrin dehalogenase hydratase hydrolysis hydrolyzed immobilized industrial inhibitors intermediate isolated ketone kinetic resolution Lett lipase metabolism method microbial Microbiol microorganisms molecular mutant NHase nitrilases nitrile nucleophile OH OH OH organic solvents Organic Synthesis oxide peptidases prochiral protease protein Pseudomonas pyruvate racemic reaction reactor recombinant residues Rhodococcus saturation mutagenesis Scheme screening selectivity sequence stability stereoselectivity strategy structure substrate substrate specificity synthetic Tetrahedron thermostability transaminase whole cells Wiley-VCH Verlag yield