Causation and Disease: A Chronological Journey

Voorkant
Springer Science & Business Media, 1993 - 238 pagina's
A historical review of the evolution of concepts, postulates and guidelines concerning disease causation from early germ theory to current work in the area of chronic noncontagious diseases. Students and researchers in epidemiology, clinical medicine, microbiology and related fields will value discussion of changing criteria as these apply to speci

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Inhoudsopgave

Concepts and Background of Causation Causality in the Natural Sciences
1
Concepts of Contagion
2
Epidemiology and Causation
3
Scurvy
4
Cholera
5
Puerperal Sepsis
7
The Age of Bacteriological Discovery
8
References
11
Limitations of the Henle Koch Postulates Effect of New Concepts and of Technology
123
Factors Directly Limiting the HenleKoch Postulates as Originally Stated
124
Introduction
128
Bacteriology
129
Virology
132
Immunology
140
References
142
Challenges to the Epidemiology of Infectious Diseases in the Next Decade
147

Causation and Bacterial Diseases
13
Edwin Klebs
15
Robert Koch
18
New Diseases
31
Legionnaires Disease
32
Lyme Disease
34
References
37
Causation and Acute Viral Diseases
41
The Epidemiological Concept
43
Agents in Search of Disease
46
Acquired Immunodeficiency Syndrome AIDS
53
References
65
Slow and Persistent Viral Infections Introduction
69
Chronic CNS Diseases Due to Conventional Viruses
76
Subacute Sclerosing Pan Encephalitis SSPE
77
New Challenges
79
Summary
83
References
84
Viruses and Cancer
87
Burkitts Lymphoma
91
Nasopharyngeal Carcinoma
95
Hodgkins Disease
96
NonHodgkins Lymphoma
97
Hepatitis B Virus HBV and Hepatocellular Carcinoma HCC
98
Genital Herpes Papillomaviruses and Cervical Cancer
101
Human Tcell Leukemia Virus Type I HTLVI and Tcell Leukemia
105
Summary
107
References
108
Causation of Epidemics and Immunological Diseases
113
Immunological Diseases
115
Immunological Nature of a Disease
116
Relation of Pathological Changes to Autoimmunization
118
Criteria for ImmuneMediated Disease
120
Other Infectious Agents
151
Immunization Programs
154
Emergence of New Viruses and New Viral Infections
158
Early Diagnosis and Detection
162
Other Challenges in Infectious Disease Epidemiology
164
References
165
Causation and Chronic Diseases
167
Toward a Unified Concept
172
References
175
Causation and Occupational Diseases Introduction
177
Epidemiological Issues
178
Legal Issues
181
Causation and the Law
183
Elements of Causal Proof in the Law
184
Guidelines for Causation in Occupational Diseases
186
Limitations and Applications
194
Current Examples of Toxic Tort Litigation
196
Agent Orange
197
Swine Flu Vaccine and the GuillainBarre Syndrome
198
Possible Modifications of the System
200
Summary
203
References
204
The Clinical Illness Promotion Factor A Third Ingredient
207
Acute Infectious Diseases
208
Viruses and Cancer
210
Viruses and Chronic Disease
212
Discussion
213
References
214
Subclinical Epidemiology
215
References
227
Epilogue
229
Index
231
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Pagina 214 - Epidemiological evidence for causal relationship between Epstein-Barr virus and Burkitt's lymphoma from Ugandan prospective study.

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