Mechanisms of Memory

Voorkant
Academic, 2010 - 343 pagina's
Many who work on the cellular and molecular processes of learning and memory are tempted to throw up their hands in frustration and conclude that the problem is insoluble. Human learning and memory is likely the most highly evolved and sophisticated biological process in existence. This book represents the first step at beginning to put together the complex puzzle of the molecular basis of memory. Sweatt creates a framework of thinking about synaptic plasticity and memory at the molecular level; one which recognizes and begins to incorporate this extreme biochemical complexity into our thinking about memory. Now in its second edition this is currently the only book on the market that takes this approach.

All chapters are fully revised, and four new chapters have been added. The book is adaptable for courses for senior level undergraduates and, first and second year graduate students. It will be of use to students interested in the medical professions and graduate students interested in translational aspects of basic memory research at a time when translational research is becoming a priority area for research funding agencies in the US and internationally.
  • More than 25% new content, particularly expanding the scope to include new findings in translational research.
  • Unique in its depth of coverage of molecular and cellular mechanisms
  • Extensive cross-referencing to Comprehensive Learning and Memory
  • Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples

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Over de auteur (2010)

David Sweatt obtained his B.S. in Chemistry from the University of South Alabama before attending Vanderbilt University, where he was awarded a Ph.D. for studies of intracellular signaling mechanisms. He then did a post-doctoral Fellowship at the Columbia University Center for Neurobiology and Behavior, working on memory mechanisms in the laboratory of Nobel laureate Eric Kandel. From 1989 to 2006 he was a member of the Neuroscience faculty at Baylor College of Medicine in Houston, Texas, rising through the ranks there to Professor and Director of the Neuroscience Ph.D. program. Dr. Sweatt's laboratory studies biochemical mechanisms of learning and memory. In addition, his research program also investigates mechanisms of learning and memory disorders, such as mental retardation and aging-related memory dysfunction. He is currently the Evelyn F. McKnight endowed Chairman of the Department of Neurobiology at UAB Medical School, and the Director of the Evelyn F. McKnight Brain Institute at the University of Alabama in Birmingham. He also is a Professor the Departments of Cell Biology, Genetics, and Psychology at UAB. Dr. Sweatt has won numerous awards and honors, including an Ellison Medical Foundation Senior Scholar Award, and election as a Fellow of the American Association for the Advancement of Science. This year he won (along with Michael Meaney and Catherine Dulac) the Ipsen Foundation International Prize in Neural Plasticity, one of the most prestigious awards in his scientific field. From 1998 until 2002 he attended drawing and painting classes at the Glassell School of Art of the Museum of Fine Arts, Houston. As an artist he explores the use of painting as a medium for expressing topics of interest in contemporary biomedical research. In 2009 he published a textbook, Mechanisms of Memory, which is illustrated with original paintings and describes current models for the molecular and cellular basis of memory formation.

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