Fatigue: Neural and Muscular MechanismsSpringer Science & Business Media, 30 nov 1995 - 542 pagina's This volume describes the current state of our knowledge on the neurobiology of muscle fatigue, with consideration also given to selected integrative cardiorespiratory mechanisms. Our charge to the authors of the various chapters was twofold: to provide a systematic review of the topic that could serve as a balanced reference text for practicing health-care professionals, teaching faculty, and pre-and postdoctoral trainees in the biomedi cal sciences; and to stimulate further experimental and theoretical work on neurobiology. Key issues are addressed in nine interrelated areas: fatigue of single muscle fibers, fatigue at the neuromuscular junction, fatigue of single motor units, metabolic fatigue studied with nuclear magnetic resonance, fatigue of the segmental motor system, fatigue involving suprasegmental mechanisms, the task dependency of fatigue mechanisms, integrative (largely cardiorespiratory) systems issues, and fatigue of adapted systems (due to aging, under-and overuse, and pathophysiology). The product is a volume that provides compre of processes that operate from the forebrain to the contractile proteins. |
Inhoudsopgave
MYOFIBRILLAR FATIGUE VERSUS FAILURE OF ACTIVATION | 25 |
MECHANISMS OF EXCITATIONCONTRACTION COUPLING RELEVANT TO SKELETAL MUSCLE FATIGUE | 41 |
THE ROLE OF INTRACELLULAR ACIDOSIS IN MUSCLE FATIGUE | 53 |
ROLE OF INTERSTITIAL POTASSIUM | 65 |
Fatigue at the Neuromuscular Junction | 77 |
FATIGUE AT THE NEUROMUSCULAR JUNCTION Branch Point vs Presynaptic vs Postsynaptic Mechanisms | 79 |
THE ROLE OF THE SARCOLEMMA ACTION POTENTIAL IN FATIGUE | 97 |
SINGLE FIBER ELECTROMYOGRAPHY IN STUDIES OF NEUROMUSCULAR FUNCTION | 105 |
SINGLETRIAL READINESS POTENTIALS AND FATIGUE | 291 |
THE SENSES OF EFFORT AND FORCE DURING FATIGUING CONTRACTIONS | 301 |
TRYPTOPHAN 5HYDROXYTRYPTAMINE AND A POSSIBLE EXPLANATION FOR CENTRAL FATIGUE | 311 |
Task Dependency of Fatigue Mechanisms | 317 |
THE SIGNIFICANCE OF MOTOR UNIT VARIABILITY IN SUSTAINING MECHANICAL OUTPUT OF MUSCLE | 319 |
INTRAMUSCULAR PRESSURES FOR MONITORING DIFFERENT TASKS AND MUSCLE CONDITIONS | 335 |
TASKDEPENDENT NATURE OF FATIGUE IN SINGLE MOTOR UNITS | 347 |
TASKDEPENDENT FACTORS IN FATIGUE OF HUMAN VOLUNTARY CONTRACTIONS | 357 |
Fatigue of Single Motor Units | 117 |
INTRINSIC PROPERTIES OF MOTONEURONS Implications for Muscle Fatigue | 119 |
NEUROMUSCULAR FREQUENCYCODING AND FATIGUE | 131 |
HUMAN MOTOR UNITS STUDIED BY SPIKETRIGGERED AVERAGING AND INTRANEURAL MOTOR AXON STIMULATION | 143 |
HUMAN MOTOR UNITS STUDIED BY INTRAMUSCULAR MICROSTIMULATION | 157 |
Fatigue Studied with NMR Techniques | 169 |
BIOENERGETICS AND MUSCLE CELL TYPES | 171 |
METABOLIC CORRELATES OF FATIGUE FROM DIFFERENT TYPES OF EXERCISE IN MAN | 181 |
MECHANISMS OF HUMAN MUSCLE FATIGUE Quantitating the Contribution of Metabolic Factors and Activation Impairment | 191 |
EMERGING OPPORTUNITIES WITH NMR | 207 |
VARIABLEFREQUENCY STIMULATION PATTERNS FOR THE OPTIMIZATION OF FORCE DURING MUSCLE FATIGUE Muscle Wisdom an... | 223 |
OVERVIEW POTENTIAL ROLE OF SEGMENTAL MOTOR CIRCUITRY IN MUSCLE FATIGUE | 237 |
THE FUSIMOTOR SYSTEM Its Role in Fatigue | 255 |
ROLE OF MUSCLE AFFERENTS IN THE INHIBITION OF MOTONEURONS DURING FATIGUE | 267 |
The Case for Central Fatigue | 275 |
CENTRAL FATIGUE Critical Issues Quantification and Practical Implications | 277 |
Integrative Systems Issues | 377 |
FATIGUE AND THE DESIGN OF THE RESPIRATORY SYSTEM | 379 |
AN INTEGRATIVE VIEW OF LIMITATIONS TO MUSCULAR PERFORMANCE | 389 |
RESPIRATORY MUSCLE FATIGUE | 397 |
FATIGUE OF JAW MUSCLES AND SPEECH MECHANISMS | 411 |
Fatigue of Adapted Systems Overuse Underuse and Pathophysiology | 423 |
FATIGUE IN ADAPTED SYSTEMS Overuse and Underuse Paradigms | 425 |
ASSOCIATIONS BETWEEN MUSCLE SORENESS DAMAGE AND FATIGUE | 453 |
MUSCLE FATIGUE IN OLD ANIMALS Unique Aspects of Fatigue in Elderly Humans J A Faulkner and S V Brooks | 467 |
HISTORICAL PERSPECTIVE A FRAMEWORK FOR INTERPRETING PATHOBIOLOGICAL IDEAS ON HUMAN MUSCLE FATIGUE | 477 |
FATIGUE BROUGHT ON BY MALFUNCTION OF THE CENTRAL AND PERIPHERAL NERVOUS SYSTEMS | 491 |
| 511 | |
CONTRIBUTORS | 523 |
INDEX | 529 |
Overige edities - Alles bekijken
Veelvoorkomende woorden en zinsdelen
acid acidosis Acta Physiologica Scandinavica action potential activation adaptation afferent feedback amplitude Applied Physiology axonal Bigland-Ritchie Brain Research Ca2+ cells central fatigue changes Chapter colleagues concentration decline decrease diaphragm discharge rate effects endurance Enoka exercise Experimental factors failure fast-twitch fatiguing contractions fiber types fibres frequency function Gandevia SC gastrocnemius glycogen human muscle increase inhibition interneurons intracellular intramuscular isometric contractions Journal of Applied Journal of Neurophysiology Journal of Physiology Kernell M-wave maximal voluntary contractions McComas mechanisms membrane metabolic motoneuron discharge motoneurons Muscle & Nerve muscle afferents muscle fatigue muscle fibers muscle spindle muscular myosin neuromuscular junction neuromuscular transmission normal output oxygen patients peripheral Physiology London pressure recruitment reduced reflex respiratory responses sarcoplasmic reticulum single motor units Sjøgaard skeletal muscle slow soleus soleus muscle spinal studies submaximal sustained tetanic force twitch force velocity Vøllestad Westerblad Woods JJ
Populaire passages
Pagina 511 - I often say that when you can measure what you are speaking about and express it in numbers you know something about it; but when you cannot measure it, when you cannot express it in numbers, your knowledge is of a meagre and unsatisfactory kind: it may be the beginning of knowledge, but you have scarcely, in your thoughts, advanced to the stage of science, whatever the matter may be.