Birkhäuser, 7 mrt. 2013 - 406 pagina's
J. M. Polak and S. R. Bloom For some time Experientia has published, as a unique feature, interdis ciplinary multi-author reviews, giving a comprehensive overview of sub jects regarded as 'growing edges' of science. The enthusiasm shown by the readers was contagious and thus it was felt necessary to compile a special volume dealing with the novel aspects of regulatory peptides. This book covers some of the growing areas in regulatory peptide research and, although it is based on the original volume of Experientia, it is expanded and updated. The topic of 'regulatory peptides' is relatively young and has grown at an unprecedented pace, from the embryonic conception of 'gut hor mones' or 'brain neuropeptides' some 15 years ago to the realisation that these active pep tides are found, almost without exception, in every part of l8 23 the body in all vertebrate and many invertebrate species • Why the term 'regulatory peptides'? It represents a convenient label encompassing both the active peptides present in nerves, which are re leased as (putative) neurotransmitters, and those in endocrine cells, which act locally or at a distance as circulating hormones, these being the l8 main components of the so-called diffuse neuroendocrine or APUD 17 system • Morphological studies support this physiological viewpoint.
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Burrin L O Uttenthal G P McGregor and S R Bloom
Penschow J Haralambidis P E Darling I A Darby
Palacios and M M Dietl
Su and J M Polak
J S Hassall T G J Allen B S Pittam and G Burnstock
P Davenport R G Hill and J Hughes
Overige edities - Alles weergeven
Acad adrenergic airway antibodies antigens autoradiographic axons binding sites bladder Bloom bombesin Brain Res calcitonin gene-related peptide capsaicin cell bodies CGRP cholecystokinin cholinergic ciliary coexistence culture Cytochem density detected distribution dorsal root effects endocrine cells enkephalin enteric neurons enteroglucagon enzyme factor fibres fluorescent function galanin ganglia ganglion cells gastrin gastrointestinal gene guinea pig Histochem Histochemistry Hökfelt hormone human hybridisation hybridization immunocytochemical immunocytochemistry immunohistochemical immunohistochemistry innervation labelled Lett ligands localisation localization Lundberg mammalian method mRNA myenteric nerve fibers nervous system neuropeptides Neurosci neurotensin neurotransmitter opioid pancreatic pathways pelvic peptide receptors peripheral Pharmac Physiol Polak probes Proc protein rat brain regulatory peptides release retrograde secretory sections sensory sequence small intestine smooth muscle Solcia somatostatin specific spinal cord studies submucous substance Sundler sympathetic tachykinins techniques tion tissue tract transgenic transmitter tumours ultrastructural vasoactive intestinal peptide vasoactive intestinal polypeptide vesicles visceral afferent vitro