Medical Biofilms: Detection, Prevention and ControlJana Jass, Susanne Surman, James Walker John Wiley & Sons, 2 apr 2003 - 320 pagina's Biofilms are formed by microorganisms growing on surfaces and comprise a series of microcolonies interspersed with spaces through which fluids and other microorganisms move. In medicine, the primary problems are biofilms associated with implants: infections are increasingly difficult to treat with traditional antibiotics and removal of the implant often becomes essential, frequently leading to higher morbidity and mortality.
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Pagina 276 - Greenberg, EP (1994). Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. Proc. Natl. Acad. Sci. USA 91, 197-201.
Pagina 276 - Singh, PK, Schaefer, AL, Parsek, MR, Moninger, TO, Welsh, MJ, and Greenberg, EP (2000) Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms.